Levamisole is an organic compound.Levamisole is slightly soluble in water and easily soluble in organic solvents such as ethanol and ether.Levamisole has a wide range of applications. Levamisole can also be used as a flame retardant for metal materials and is also used in industries such as textiles, adhesives, and paints.A common method for preparing levamisole is to react urea with diethyl oxalate. The specific steps are to heat urea and diethyl oxalate to 155-165 degrees Celsius, react for 8-12 hours, and then perform crystallization, filtration, drying, and other steps to obtain crystals of levamisole.And the safety information about levamisole: It is a combustible substance that will burn and produce toxic gases when it encounters an open flame. During operation, care should be taken to avoid inhaling levamisole dust and avoid contact with the skin and eyes. When storing, keep away from fire and oxidants, and keep the container sealed.
Product Detail
| Property | Description |
|---|---|
| CAS No. | 14769-73-4 |
| Molecular Formula | C11H12N2S |
| Molecular Weight | 204.29 g/mol (base), 240.76 g/mol (HCl) |
| Appearance | White to grayish crystalline powder (base); white or off-white crystalline powder (HCl) |
| Melting Point | 230–233°C (base), 225–230°C (HCl) |
| Boiling Point | 344.4°C (at 760 mmHg, base) |
| Density | 1.32 g/cm³ (base) |
Key Applications & Functions
| Category | Description |
|---|---|
| Primary Mechanism | Inhibits succinate dehydrogenase in parasites, disrupting anaerobic metabolism and causing neuromuscular paralysis |
| Anthelmintic Use | - Livestock: Treats gastrointestinal nematodes (e.g., Haemonchus contortus, Ostertagia spp.) in cattle, sheep, pigs - Aquaculture: Controls ectoparasites (e.g., Dactylogyrus, Trichodina) via immersion (1–2 g/m³) or oral administration (4–8 mg/kg) |
| Immunomodulation | Enhances T-cell-mediated immunity and macrophage activity at low doses (1/4–1/3 of anthelmintic dose); used in immunodeficiency or chronic disease |
