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Product Category 03

procaine

Chinese name:普鲁卡因

English name:procaine

Chinese alias:盐酸普罗卡因;奴佛卡因;4-氨基苯甲酸 2-二乙基氨基乙基酯;2-(二乙氨基)乙基-4-氨基苯甲酸酯;奴夫卡因;4-氨基苯甲酸-2-(二乙氨基)乙酯

English alias:Procaine hydrochloride;Novocaine;4-aminobenzoic acid 2-diethylaminoethyl ester;2-(diethylamino)ethyl-4-aminobenzoate;Novocaine;4-aminobenzoic acid-2-(diethylamino)ethyl ester

CAS号:59-46-1

PSA:55.56000

LogP:2.34860

Accurate quality:236.15200

Appearance and properties:White crystalline powder

Storage conditions:0-6ºC

  • Product Details

Product Detail

PropertyDescription
CAS No.59-46-1 (free base) 
Molecular FormulaC13H20N2O2(free base)
Molecular Weight236.31 g/mol (free base) / 272.77 g/mol (HCl)
AppearanceWhite crystalline powder (free base); colorless crystals or white powder (HCl)
Melting Point61°C (free base); 153–156°C (HCl)
Boiling Point373.6°C (free base, at 760 mmHg)
Density1.1 g/cm³ (free base)
Refractive Index1.543

Key Applications & Functions

CategoryDescription
Medical UsesLocal anesthesia: Infiltration, spinal, nerve block, and surface anesthesia (mucous membranes)
Diagnostic/therapeutic nerve blocks
Dental procedures
MetabolismHydrolyzed by plasma pseudocholinesterase into para-aminobenzoic acid (PABA) and diethylaminoethanol; renal excretion
Industrial Applications- Intermediate in synthesizing dyes and agrochemicals
- Research reagent in biochemical assays (e.g., cholinesterase activity tests)

Safety and Handling

  • GHS Hazard Codes: H315 (Skin irritation), H319 (Eye irritation), H335 (Respiratory irritation)

  • Precautions: Use PPE (gloves, goggles), avoid inhalation, and work in a fume hood.

  • First Aid: Rinse eyes/skin with water; seek medical attention for ingestion or severe exposure


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